CATS is at the forefront of research in paediatric transport medicine at an international level, with numerous publications in high-impact journals and presentations at various critical care conferences.

We are part of the research group based on the PICU at Great Ormond Street Hospital and the Critical Care Research Group in the Portex Unit, Institute of Child Health, University College London (UCL).

There is a strong research ethic within the clinical service, and all staff are encouraged to undertake a research or audit project while working at CATS.

Collaborators

  • The Intensive Care National Audit and Research Centre (ICNARC), London

  • The Paediatric Intensive Care Audit Network (PICANet), University of Leeds

Current themes

  • Epidemiology of critical illness in children transported to PICU

  • Novel statistical models to predict outcome in retrieved children

  • Effects of service organisation and delivery on PICU outcome

  • Children transferred for neurosurgical intervention to PICU

  • Salbutamol toxicity in children with severe asthma

  • Adverse events during tracheal intubation

  • Optimal oxygen saturation targets in sick children

Ongoing clinical trials

       

Recent key publications

  • Inwald DP, Canter R, Woolfall K, Mouncey P, Zenasni Z, O’Hara C, Carter A, Jones N, Lyttle MD, Nadel S, Peters MJ, Harrison DA, Rowan KM; PERUKI (Paediatric Emergency Research in the UK and Ireland) and PICS SG (Paediatric Intensive Care Society Study Group)

    Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial.

    Arch Dis Child. 2018 Aug 7. pii:archdischild-2018-314924. doi: 10.1136/archdischild-2018-314924.

  • Ramnarayan P, Lister P, Dominguez T, Habibi P, Edmonds N, Canter RR, Wulff J, Harrison DA, Mouncey PM, Peters MJ; United Kingdom Paediatric Intensive Care Society Study Group (PICS-SG).

    FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): a multicentre pilot randomised controlled trial of high-flow nasal cannula therapy versus continuous positive airway pressure in paediatric critical care.

    Crit Care. 2018 Jun 4;22(1):144. doi: 10.1186/s13054-018-2080-3

  • Peters MJ, Jones GAL, Wiley D, Wulff J, Ramnarayan P, Ray S, Inwald D, Grocott M, Griksaitis M, Pappachan J, O’Neill L, Eaton S, Mouncey PR, Harrison DA, Rowan KM; Oxy-PICU Investigators for the Paediatric Intensive Care Society Study Group (PICS-SG).

    Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial.

    Intensive Care Med. 2018 Aug;44(8):1240-1248. doi: 10.1007/s00134-018-5232-7

  • Ramnarayan P, Dimitriades K, Freeburn L, Kashyap A, Dixon M, Barry PW, Claydon-Smith K, Wardhaugh A, Lamming CR, Draper ES; United Kingdom Paediatric Intensive Care Society Acute Transport Group.

    Interhospital Transport of Critically Ill Children to PICUs in the United Kingdom and Republic of Ireland: Analysis of an International Dataset.

    Pediatr Crit Care Med. 2018 Jun;19(6):e300-e311. doi: 10.1097/PCC.0000000000001506. PubMed [citation] PMID: 29432405